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Long-term supplementation (10-20 g/day for 6-9 months) showed substantial benefits, with 20 g daily improving physical component scores in females (p=0.013)

After adjustment for age, sex, apolipoprotein E 4 allele, plasma homocysteine concentration, and education level, subjects in the upper quartile of baseline plasma PC DHA levels, compared with subjects in the lower 3 quartiles, had a relative risk of 0.53 of developing all-cause dementia (95% confidence interval, 0.29-0.97