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Get the escalation wrong and you either lose efficacy or gain side effects you did not need

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NHS loading is 1mg hydroxocobalamin every two days for two weeks, then maintenance every two to three months for life when the cause is non-dietary

Understanding this mechanism matters because it explains why most GI side effects are dose-dependent, temporary, and manageable through titration strategies

It was hypothesized that this will disrupt SARS-CoV2 replication and penetration into cells

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