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For example, CRC cells exhibited upregulation of DNA repair proteins such as RAD50 and DNA-PK, which are critical for the homologous recombination and non-homologous end-joining pathways, respectively

46,775 Spatial transcriptomics Hepatocyte zonation within the liver lobule reflects significant functional variations driven by gradients of oxygen, nutrients, hormones, and Wnt morphogens

10.1016/j.neuroscience.2013.01.035 30

In the original mouse work it was described as well-tolerated, but that is the limit of the in-vivo safety evidence, and it is mouse-only

Listening to them can go a long way, he says

In tendon and ligament pathology, both peptides have shown remarkable efficacy in preclinical models of tissue repair