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doi: 10.4183/aeb.2021.449 99 TongL.ZhangX.HaoH.LiuQ.ZhouZ.LiangX.et al

Hence, KD emerges as a potentially promising strategy for cancer prevention

Recently, calcium channels namely transient receptor potential (TRP) superfamily, including members of the subfamilies A (TRAP1), M (TRPM2 and 7), and V (TRPV1 and 4), have demonstrated to play a role in the nociception mediated by sensory neurons

LPO radical can damage the macromolecules (DNA, RNA, and proteins) and can initiate cytotoxic, genotoxic, and inflammatory reactions

For instance, the secretion of interferon gamma (IFN-) by CD8+ T cells has been shown to down-regulate the expression of SLC3A2 and SLC7A11 in tumor cells, leading to a disruption in cystine uptake ( Myeloid-derived suppressor cells (MDSCs) express the transporter SLC7A11, which selectively transports cystathionine but does not export cysteine