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Fatty acid oxidation mediated by malonyl-CoA decarboxylase represses renal cell carcinoma progression

Additionally, increased cellular uptake of glucose leads to heightened mitochondrial respiration, resulting in elevated ROS production that can further inflammation and cell injury (Li et al., 2015

Forster et al., 1996

Huang XY, Wei X, Qiao SJ, Zhang X, Li R, Hu SX, et al

In addition, cancer cells chronically exposed to an acidic pH reveal a downregulation of the mitochondrial ACC2 isoform, the enzyme that regulates CPT1 activity by malonyl-CoA synthesis

No lenticular opacification was reported, therefore, combined with the results of Pitts (209), it is unclear whether UV-B irradiation produces permanent cataracts in rabbit lenses in vivo