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Therefore, inhibiting SLC7A11 can interfere with the synthesis of glutathione in tumor cells and disrupt the oxidative-reductive homeostasis of cancer cells (Zhang et al., 2018)

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8,9 Interestingly, Cyp2E1 expression in mitochondria may be critical for hepatotoxicity

To enable the continuous online monitoring of genetically-encoded probes, an in-house coupled fermentor-fluorimeter system was previously developed 34