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Gingiva-derived mesenchymal stem cells (GMSCs) possess multipotent differentiation capabilities and potent immunomodulatory/anti-inflammatory functions and have shown therapeutic potentials in various animal models of human diseases [31, 32]

It enhances their chemosensitivity to conventional therapies [230, 231]

Treatment cost is influenced by: The type of whitening method used Laser toning, glutathione therapy, carbon peel, HydraFacial whitening, and chemical peels all work differently

ROS and RNS were shown to stimulate the TRPM2 channel in intact cells (Hara et al., 2002

The ECM is mainly composed of COL II, fibres, elastin, and large amounts of proteoglycans, especially aggrecan (ACAN), with negative charge [15]

When exposed to the same amount of sunlight, individuals who are 60 years and older face a higher susceptibility to developing skin cancer compared to those who are younger than 60