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However, it is not known whether vitamin B 12 supplementation, in addition to folic acid supplementation, may be beneficial in the prevention of NTD (62) randomized controlled trials are needed to address this question

Rather than asking what is the dose, which presumes the compound is already the answer, the stronger questions open up the actual decision

Pregnancy and lactation: Maintaining normal vitamin B12 levels is especially important for pregnant and breastfeeding women, as low levels can affect fetal development and lead to developmental delays in breastfed babies

B Vitamins for Cognition November 29, 2019 Top Picks for B-12 and other B Vitamins

However, exactly how long the effects will last can vary between some patients