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For instance, amitriptyline, imipramine, and desipramine strongly inhibit 5-HT reuptake, 344 clomipramine specifically inhibits NE reuptake, and nortriptyline can inhibit both NE and 5-HT reuptake while also exerting central anticholinergic effects

This process consists of ROS that appear to damage cellular membrane polyunsaturated fatty acids, resulting in the formation of toxic lipid peroxidation compounds [11]

Adaptation to unfavorable environmental conditions is associated with the expression of many genes (Ryan et al., 2009

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Finally, using online tools MetaboAnalyst 5.0 [40] and FELLA package (version 1.14) [41] to determine the differences in metabolite pathways of enrichment and analysis

During the bodys normal functioning an excess of oxygen containing molecules are produced, these molecules are typically very reactive with other molecules they come in contact with