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Bypassing mitochondrial complex III using alternative oxidase inhibits acute pulmonary oxygen sensing

Targeting these mechanisms may result in novel therapeutic approaches aimed at developing the means of effective prevention and treatment of the core ASD symptoms [11]

The ipratropium-bound structure demonstrates how OCTN2 binds positively charged drugs We selected the anticholinergic bronchodilator, ipratropium, as a model compound to investigate how OCTN2 binds positively charged drug molecules

Abnormally elevated biomarkers of organ dysfunction in the blood, including creatine phosphokinase, aspartate aminotransferase, and alanine aminotransferase, are corrected upon choline repletion