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In ongoing phase 3 clinical trials, dosing starts at 0.25 mg per week alongside semaglutide, with gradual increases reaching a maximum of 2.4 mg weekly by the 17th week, following a 16-week dose-escalation protocol [16]

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[37] Brown V, Patel K, Viskaduraki M, et al

[DOI] [PMC free article] [PubMed] [Google Scholar] 256.Jones K, Rivera C, Sgadari C, Franklin J, Max EE, Bhatia K, et al

Zdecydowana wikszo danych pochodzi z bada in vivo przeprowadzonych na modelach mysich i szczurzych, a take z eksperymentw in vitro na hodowlach komrkowych