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The cellular necrosis after an APAP overdose leads to release of cell contents, which includes molecules termed damage-associated molecular patterns (DAMPs) that can bind to pattern recognition receptors, e.g., toll like receptors, on macrophages and trigger formation of various cytokines and chemokines [8690]

HPV16 drives cancer immune escape via NLRX1-mediated degradation of STING

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Preparation and evaluation of inhalable dry powder containing glucosamine-conjugated gefitinib SLNs for lung cancer therapy