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Mitochondrial oxidative stress causes mitochondrial fragmentation via differential modulation of mitochondrial fission-fusion proteins

Useckaite and colleagues in year 2020, examined the content of EVs from CF bronchial epithelial cells (CFBE41o-) and found that these vesicles were notably enriched with proteins linked to acute inflammatory stress and infection in CF lung disease [6]

Pedret A, Valls RM, Caldern-Prez L, Llaurad E, Companys J, Pla-Pag L, et al

J Nutr 138:14321436

This leads to the development of malignant tumors, like hepatocellular carcinoma (HCC) (Gerdemann et al

doi: 10.1067/mob.2003.99 [DOI] [PubMed] [Google Scholar] 4.Dandolu V, Singh R, Lidicker J, et al