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Outcomes after oncoplastic breast-conserving surgery in breast cancer patients: a systematic literature review

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95 conducted the single-center, randomized, placebo-controlled, triple-blind ZODIAK trial included 86 patients aged 40 to 70 with symptomatic tibiofemoral OA to assess the efficacy of biannual infusions of zoledronic acid (ZA) in influencing cartilage thickness, joint space narrowing, and BML size over a 24-month period alongside clinical outcomes such as pain scores and quality of life measures

Interleukin-6 plays an essential role in hypoxia-inducible factor 2-induced experimental osteoarthritic cartilage destruction in mice