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Finally, there are two isoforms of SHMT in mammals, one cytoplasmic and the other mitochondrial 45,59,66 , and the same might be true for worms

doi: 10.3797/scipharm.1408-16 166 NeagMAMocanAEcheverriaJPopRMBocsanCICrisanGet al

Biochem Biophys Res Commun 438:721727 Li F, Rajendran P, Sethi G (2010) Thymoquinone inhibits proliferation, induces apoptosis and chemosensitizes human multiple myeloma cells through suppression of signal transducer and activator of transcription 3 activation pathway

Despite decades of research, no cure exists, and current treatments focus primarily on symptom management rather than altering the disease trajectory (Sun and Zhang, 2024)

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