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CD154/CD40 Another pair of co-stimulatory receptor-ligand system whose engagement has profound effects on B, dendritic and endothelial cells is the CD40-CD40 ligand (CD154)

Kt qu l khng ch khin da lo ha nhanh m cn nhn nheo, sn si, km sn chc v nhiu vn khc

Under the influence of biological activity, chemical reactions, and physical forcesincluding hydrolysis and ultraviolet exposureplastic debris gradually fragments, giving rise to MPs/NPs 2,3,4

Wang M, Wang B, Wang S, Lu H, Wu H, Ding M, Ying L, Mao Y, Li Y

Substrate supplementation alone may have limited impact on the tightly regulated NO pathway

Based on these limitations, future research should integrate detailed exposure metrics, genetic profiling, and chronotype assessments to better clarify mechanisms and identify high-risk subgroups