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Though non-specific, certain pathogenic factors including genetic predisposition, visceral hypersensitivity, food intolerance, altered gut-brain axis and gut dysmotility, dysfunction of innate immunity and dysbiosis may contribute to this disorder (Figure 1)

Important Information: Potential Side Effects: Long-term use of glutathione has been associated with a decrease in zinc levels

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Methylation cycle optimization, if indicated, is an efficient avenue to dramatically improve health and mental well being in many children and adults suffering a wide range of symptoms and problems