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Acta 1844 , 14531462 (2014)

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10.1016/j.bbapap.2016.02.006 Biochim

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2023;39:e20230003

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However, recent evidence suggests that redox dysregulation may be an important or even primary trigger of a cascade of events leading to neurodegeneration

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Quercetin-triggered Ca2+ signaling consists of both internal Ca2+ release and extracellular Ca2+ influx, and most importantly, quercetin-induced Ca2+ release from the ER, and as a result, inositol IP3R inhibition by xestospongin C blocked quercetin-induced Ca2+ release

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(2016) [] provided evidence of decreased antioxidant enzyme activity and increased lipid peroxidation products in rats exposed to lead that are indicative of oxidative stress in these rats

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