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Physiological Effects of the Mitochondria: The healthy function of mitochondria is essential to life-sustaining metabolic processes, including: (1, 5) Regulating ion concentrations, such as calcium buffering critical to intracellular communication Maintain roles in fluctuating lipid levels Synthesizing products necessary for the transportation of glucose and insulin Providing sufficient energy for blood flow to and within the heart Regulating the removal of cellular damage or apoptosis if the condition is deleterious enough to the mitochondrions function Mitochondria Dysfunction and Health: Now that research has enlightened our concept of how the mitochondria are more than just energy generators, the medical community now has a new field of research to investigate how mitochondria functional defects adversely affect human health

Therefore, modulation of gut microbiota mechanisms might be the key to symptom relief of MDD

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