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Through this activity, BCAA supplementation ameliorates the impaired dendritic spine formation and synaptic responses caused by various genetic defects, including those displayed by Nf1 +/ , Cttnbp2 +/M120I , and Vcp +/R95G mice [14,17,18]

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In addition, the use of cell lines or mouse models has facilitated the investigation of gene expression and diet-induced beta cell dysfunction (150, 151)

Lipid peroxidation plays a multifaceted role in regulating pyroptosis, as it is involved in both promoting and inhibiting this pyroptotic pathway under different physiological and pathological conditions