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The peptide also modulates serotonergic and dopaminergic systems, which has implications beyond mood

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As a result, the transcription of the COL3A1 and COL1A1 genes, which produce type III and I collagen precursors, is reduced, ultimately leading to a decrease in the amount of type III and I collagen present in the skin (44)

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Introduction Colorectal cancer (CRC) ranks as the third most commonly diagnosed malignancy worldwide, with approximately 1.93 million new cases and 904,000 deaths in 2022 [1]