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Conflict of interest MK reports grants from GlaxoSmithKline plc, Mitsubishi Tanabe, Astellas, Sanofi, Taisho Pharmaceutical, NIPPON SHINYAKU CO., LTD., and Taiju Life Social Welfare Foundation, outside the submitted work

Clonal hematopoiesis-related mutant ASXL1 promotes atherosclerosis in mice via dysregulated innate immunity

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During macrophage development, ATF4 serves as a master regulator to govern monocytes differentiation to gut-resident macrophages (gMac)

However, sufficient pre-clinical and clinical data exist to justify well-designed clinical trials of antioxidants in COPD