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The research-grade version, TB 500 Thymosin Beta-4 Fragment 5mg, isolates the active tetrapeptide sequence Ac-SDKP (N-acetyl-seryl-aspartyl-lysyl-proline), which is believed to be responsible for much of T4s biological activity

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GHR binding induces receptor dimerisation and activation of the associated Janus kinase 2 (JAK2), triggering a phosphorylation cascade that activates Signal Transducer and Activator of Transcription 5 (STAT5) the primary transcriptional mediator of GHs genomic effects, including IGF-1 gene expression

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