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de novo lipogenesis, impaired fatty acid oxidation, inflammasome activation, and mitochondrial dysfunction, all of which exacerbate hepatic steatosis and injury ( Notably, bioactive metabolites derived from TCM have gained attention for their ability to modulate AMPK-mediated pathways

Effects of pyrroloquinoline quinone and imidazole pyrroloquinoline on biological activities and neural functions

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Changes in muscle mass and function were evaluated in 55 pre-cachectic and cachectic patients with lung cancer, who received an oral nutritional supplement containing 200 kcal, 10 g whey protein, 2.0 g eicosapentaenoic acid/docosahexaenoic acid in fish oil, and 10 g 25-hydroxy-vitamin D3 during a 12-week randomized, double-blind, controlled pilot trial