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Disruption of mitochondrial function and cellular ATP levels by amiodarone and N-desethylamiodarone in initiation of amiodarone-induced pulmonary cytotoxicity

The column was washed with acetonitrile for 10 min followed by a linear gradient back to the initial mixture of 30% acetonitrile with the flow rate 1 ml/min

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Perform principal component analysis (PCA) and use the first 10 PCs to construct a SNN network

Glutathione supports both Phase I and Phase II liver detoxification, with GSH conjugation constituting a major elimination pathway for drugs, metabolic waste products, and environmental toxins

[DOI] [PMC free article] [PubMed] [Google Scholar] 23.Gonzlez-Cofrade L., de Las Heras B., Apaza Ticona L., Palomino O.M