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Med 79, 207214 (2022)

Research demonstrated that immunological targeting by HSPs could be a potential pathogenic mechanism of neuropathy following SARS-CoV-2 infection [33]

However, this commitment is not absolute

Spine (Phila Pa 1976) 24 (23), 24192425

Other gene mutations, such as MTHFR A1298C, chronic bacterial infections, and aluminum, can also lead to low BH4 levels

This limitation does not undermine the studys value in identifying a novel regulatory axis but highlights the need for follow-up experiments to strengthen mechanistic claims