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Rorsman, P., Ramracheya, R., Rorsman, N

Considering that Nrf2 signaling plays an important role in maintaining redox equilibrium, its involvement in the protection against oxidative stress induced by heavy metals, including mercury, has a rational basis (Buha et al

doi: 10.3390/cancers14133142 29

Role of the Keap1/Nrf2 pathway in neurodegenerative diseases

Animal and in vitro experiments have further verified its barrier repair effect: Butyrate can promote proliferation and mucin secretion of intestinal epithelial cells (IPECs, Caco-2, HT-29), enhance the expression of tight-junction proteins (ZO-1, Claudin-1, Claudin-2), and maintain colonic mucosal integrity ( Clostridium mixtures modulate microbiota composition (e.g., Lactobacillus, Oscillospira ) to mitigate antibiotic-induced dysbiosis, reduce pathogenic bacterial translocation, and alleviate DSS-induced UC in mice ( CB -derived extracellular vesicles (EVs) decrease intestinal Escherichia coli/Shigella levels, enhance barrier integrity, and relieve UC symptoms ( CB, when combined with Akkermansia muciniphila , synergistically enhances barrier repair and increases sensitivity to anti-PD-L1 immunotherapy

Examination of the efficacy of acute L-alanyl-L- glutamine ingestion during hydration stress in endurance exercise