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doi: 10.1016/j.ijrobp.2020.12.019 356 LiangSHuDLiGGaoDLiFZhengHet al

Economou JS, Essner R, Rhoades K, Yamada T, Swisher SG , Holmes EC, Golub S, Morton DL

Neither route has been directly compared for safety in clinical trials

This systematic study showed that phytochemicals inhibit the release or activity of mast cells, such as histamine, inhibit the secretion of Th2 cytokines, such as IL-4, IL-5, IL-13, and GATA-3, and reduce IgE levels as well as macrophages and lymphocytes