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doi: 10.1093/jnci/djw236 215 ZhangDTaiLKWongLLChiuLLSethiSKKoayES

Oral bacteria, particularly those implicated in periodontitis, stimulate the production of pro-inflammatory cytokines, which further drive the growth of pathogenic oral bacteria and contribute to gut inflammation 8,47

PLoS One 6(7):e22094 Tsai W-C, Hsu S-D, Hsu C-S, Lai T-C, Chen S-J, Shen R, Huang Y, Chen H-C, Lee C-H, Tsai T-F, Hsu M-T, Wu J-C, Huang H-D, Shiao M-S, Hsiao M, Tsou A-P (2012) MicroRNA-122 plays a critical role in liver homeostasis and hepatocarcinogenesis

Only in severe deficiency cases, neurological complications can indirectly contribute to joint discomfort

Szeto HH, & Birk AV

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