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For instance, lactose intolerance can lead to bloating and cramping after consuming dairy products, while gluten sensitivity may trigger similar symptoms after eating wheat-based foods

An alternative explanation for the lack of NRF2 response could be the epigenetic silencing of redox genes

Via the catalytic activity of a broad superfamily of phase II detoxification enzymes, the Glutathione STransferases (GSTs), glutathione is covalently conjugated to electrophilic xenobiotics and endogenous reactive intermediates

Anesthesiology, 58: 11-17

What to expect after use

Watch for early warning signs such as: Dark-colored urine Dry mouth Fatigue Muscle cramps Headache Feeling lightheaded or dizzy Reduced performance during work or exercise The best way to stay ahead of dehydration is to drink fluids consistently throughout the day, replace electrolytes during prolonged sweating, take breaks in the shade or air conditioning, and recognize when symptoms require medical attention