The most recent study reported that miR-491-5p was downregulated in both CRC tissues and cell lines and its overexpression reduced proliferation in vitro and tumor growth in vivo (103)
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Degradation can occur through several pathways, including the ubiquitin proteasome system (UPS) or various forms of autophagy, including macro-autophagy or chaperone-mediated autophagy (CMA)
A subset of dorsal neurons modulates circadian behavior and light responses in Drosophila

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