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The weight gain, feed intake, feed conversion ratio (FCR), and cell-mediated immune response were monitored after the injection of 0.1 mL of 10% phytohemagglutinin (PHA)

Selenium deficiency can be caused by intestinal malabsorption or increased loss through diarrhea, which may be symptoms of cancer or can be associated with anti-cancer treatment (including radiotherapy and gastrointestinal surgery) (376, 377)

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Dabigatran is measured with a pharmacodynamic assay, the TT (qualitative) or dilute thrombin time (dTT), the latter of which can be calibrated to provide dabigatran-specific concentrations45

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The day before the experiment, cells were seeded in black, 384-well clear bottom plates (Corning) at a density of 1,000 cells/well using a Beckman Biomek FX Workstation