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The peptide interacts with the nitric oxide (NO) system, modulating vascular tone and cell signaling at the microenvironmental level to support the transition from the inflammatory phase to the proliferative phase of healing

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Considering the important role of the above aspects in PNI, it is feasible to explore the mechanism of PNI by studying the interaction between cancer cells and nerves, the expression of neurotrophic factors, and the invasion and migration ability of cancer cells in the process of PNI