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Glutamine and glutamate can trigger triglyceride accumulation in macrophages, whereas glycine, alanine, leucine, and cysteine can downregulate triglyceride levels (Rom et al., 2017)

Ent1 and Ent2 are APs with modular domain architecture, displaying an epsin N-terminal homology (ENTH) domain followed by unstructured regions containing several interaction motifs: two Ubiquitin Interaction Motifs (UIMs), two Asn-Pro-Phe motifs (NPF) responsible for interacting with EH (Eps-15 Homology) domains of Ede1, and a C-terminal CBM

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