intestinal microbiota metabolism of l carnitine A schematic drawing to demonstrate gut bacterial dietary Gut microbiota metabolism of l-carnitine

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[15] This is exactly the biological logic that made the local MGF splice variant interesting in the first place: nature appears to use a transient, compartmentalized IGF-1 signal for repair, precisely to avoid the metabolic disturbances that broad, sustained IGF-1 receptor activation would cause including effects on glucose homeostasis

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But in the process, they generate reactive oxygen species (ROS), unstable molecules that can damage DNA, proteins, and lipids