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Additionally, they can be used to manage liver disease, cancer, and HIV/AIDS

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PCS also induces apoptosis and autophagy by activating NF-B and MAPK signaling and increasing the phosphorylation of extracellular signal-regulated kinase (ERK), p38, and c-Jun N-terminal kinase (JNK) in HK-2 cells ( Figure 3 ) [117]

Notably, conflicting findings have been reported regarding the abundance of certain bacterial taxa (e.g., Megasphaera and Barnesiella ), potentially due to population heterogeneity, methodological variability, or confounding factors such as constipation and allergies (Zhao et al., 2019

Glutathione brightening: At 5%, glutathione inhibits melanin production to fade dark spots and post-acne marks

Therefore, alteration of the GSH/GSSG ratio appears to be a common factor in the regulation of macrophage and cell-autonomous cellular inflammation