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Understanding the fine-tuned regulatory mechanisms of these interactions is crucial for precise intervention in ferroptosis

However, these combination therapies have not shown a significant increase in overall survival compared to chemotherapy alone [35,36,37,38]

Interestingly, ADNP mutations were found in postmortem AD olfactory bulbs and hippocampi [348]

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Metabolic research has shown improvements in insulin sensitivity and glucose metabolism in some models, suggesting potential applications in metabolic syndrome and age-related metabolic dysfunction