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SAR650984, a novel humanized CD38-targeting antibody, demonstrates potent antitumor activity in models of multiple myeloma and other CD38+ hematologic Malignancies

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Notably, clinical trial involving the use of Daratumumab and Atezolizumab (anti-PDL1) (NCT03023423) was also halted due to the lack of clinical efficacy ( 5 Conclusions Despite the small sample size, this study has important clinical implications in the treatment of NKTL patients

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Table 15: Efficacy Results in PARAMOUNT Figure 8: Kaplan-Meier Curves for Overall Survival in PARAMOUNT Treatment of Recurrent Disease After Prior Chemotherapy The efficacy of pemetrexed for injection was evaluated in Study JMEI (NCT00004881), a multicenter, randomized (1:1), open-label study conducted in patients with Stage III or IV NSCLC that had recurred or progressed following one prior chemotherapy regimen for advanced disease