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This outcome highlights the need for further investigation into the role of iron deposition in the pathophysiology of PD

doi: 10.1038/ncb3593 47 ChaYHanMJChaHJZoldanJBurkartAJungJHet al

Hypomethylation of promoter regions can lead to overexpression of genes which play a key role in cell proliferation, differentiation and apoptosis

27 , 17261741.e1725 (2019)

Following infection, the viral DNA integrates into the host genome to disrupt normal cell function

Intriguingly, in the CoPP:GSH/ADPVO-bound dataset, only a small subset of particles (8.9%) adopted the expected occluded conformation with a closed NBD dimer (Supplementary Fig 9)