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Within MSFraggers, precursor mass tolerance was set to +/-20ppm, fragment mass tolerance was set to +/-20ppm, tryptic cleavage specificity was applied, as well as fixed methionine oxidation and fixed N-terminal acetylation

Unlike older GHRPs (like GHRP-2 or GHRP-6), Ipamorelin has a stellar safety profile in research settings because it shows very little to no effect on other hormones like cortisol or prolactin

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Exenatide (Byetta), approved in 2005, was based on exendin-4, a naturally occurring peptide from the Gila monster with inherent DPP-4 resistance