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Thus, our data suggest a previously unknown pathogenic role of increased VEGFA for cataract formation, which may promote cataractogenesis by increasing oxidative damage and ERK hyperactivation in the lens

Blumenreich M, Andreeff M , Murphy ML, Young C, Clarkson B

Vigorous agitation shears molecular chains and accelerates aggregation

Consequently, the response of brain tissue to radiation may differ between rodent preclinical models and human patients, particularly at the molecular level