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As a tumor suppressor, YY2 negatively regulates de novo serine synthesis by binding to the PHGDH promoter and repressing its transcriptional activity, thereby inhibiting tumorigenesis (104)

The physician will use a type of x-ray machine called a fluoroscope to help guide a small needle to the correct location in the piriformis muscle

Cell Culture HeLa cells were obtained from the Lerner Research Institute of the Cleveland Clinic Foundation (Cleveland, OH)

Safety, efficacy, and pharmacodynamics of the investigational agent orteronel (TAK-700) in metastatic castration-resistant prostate cancer (mCRPC): updated data from a phase I/II study [abstract 98]

A study published in the Archives of General Psychiatry documented similar findings one year later in a 4-week-long Xanax withdrawal trial

In animal studies, metabolic improvements were observed over weeks to months, not days