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Finally, eriodyctiol is hydroxylated and converted to quercetin (Figure 1) using flavanol synthase ( Figure 1 Biology of Quercetin Flavonoid compounds, such as quercetin, were initially studied for their biological activity in affecting capillary wall resistance ( in vitro and in vivo ( in vitro and in vivo models including: inhibition of platelet aggregation ( in vitro and in vivo , when administered either alone or with absorption enhancer HP--CD ( Beneficial Effects of Vitamin C and Quercetin in Viral Infections There is a tremendous amount of literature supporting the antiviral properties of quercetin, in both in vitro and in vivo experiments