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Upon activation, HSF1 trimers translocate to the nucleus and bind to heat shock elements (HSEs) in the promoters of target genes, thereby increasing the transcription of HSP70s, which then undergo degradation or re-monomerization (Vihervaara and Sistonen, 2014)

United States Pharmacopeial Convention

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(2011) Am J Prev Med, 41: 357

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