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As increased hyperresponsiveness and neutrophilia are driving forces of immunopathology associated with Candida infections 10,83,84,85 , it is tempting to speculate that albumin-induced 13-HODE release by the fungus may be a contributing factor

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In addition, the CAP-Gly2 and CAP-Gly3 domains have been reported to bind to ubiquitin (Supplementary Fig

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Additional evidence suggests that electrophiles also cause cytotoxicity by depleting the cellular GSH pool, which can initiate redox imbalance or accelerate ongoing oxidative stress

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