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Per the commenter, ReActiv8 addresses the root cause of pain for patients experiencing multifidus muscle dysfunction through efferent stimulation of the medial branch nerve of the dorsal ramus, triggering the multifidus muscle to contract, which over time, improves the multifidus' ability to stabilize the spine

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doi: 10.1038/nature14156 112 MotwaniMFitzgeraldKA

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Any oral supplement must be ingested and absorbed through your digestive tract