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This was performed with brain photographs before the application and at intervals after the application for both control and treated animals

Research in cell and animal models demonstrates its capacity to suppress NF-kB activation, reduce pro-inflammatory cytokine release including IL-1b, TNF-alpha, and IL-6, and interact with melanocortin receptors on immune and intestinal epithelial cells

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Second, it induces the production of heme oxygenase-1, a protective enzyme, along with heat shock proteins such as HSP-60, HSP-70 and HSP-90

Directions for use: Work into a rich lather and use all over your Face and body, before rinsing off

All the authors contributed to the study and approved the manuscript for publication