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By contrast, it is widely acknowledged that the resident macrophage population plays a more crucial role in POI [80]

The degenerative process of intervertebral discs is often accompanied by the overexpression of matrix metalloproteinases (MMP3, MMP13) and inflammatory factors (IL-1, IL-6, IL-8, PEG2, TNF-) (Wang et al., 2020)

doi:10.3390/antiox9070624

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