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Cluster 3 includes PTGS1, PTGS2 , and ALOX5 involved in prostaglandin metabolism and leukotriene receptor activity, whereas Cluster 4 ( MMP9, MMP2, ITGB8, LOX, TIMP2, and VCAM1 ) and Cluster 5 ( MMP9, MMP2, LOX, TIMP2 ) were found to trigger extracellular matrix organization, elastic fiber formation, and matrix metalloproteinases activity

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Acknowledgements This work was supported by U.S

A comprehensive understanding of the physiological properties of the BBB and how it alters under pathological conditions has also been investigated

Extracellular vesicles engineered with valency-controlled DNA nanostructures deliver CRISPR/Cas9 system for gene therapy

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