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Thus, the dosage in individual cases was modulated to avoid the occurrence of specific clinical side effects or blood exam abnormalities (headache and insomnia, weight changes, age, neutropenia, alteration of liver function indices, hypercholesterolemia, gastrointestinal disturbances) by adjusting to maximal dosage without side effects, as required for off-label drug administration

Front Microbiol 13

Two to six times more ynfA gene expression than tolC gene expression was observed (Sarkar et al., 2015)

In the face of controversies and challenges, it is essential to establish a more efficient translational interface between science, technology, and clinical practice, driving mitochondrial metabolic reprogramming therapy from a potential pathway to clinical reality. Conclusion Mitochondrial metabolic reprogramming plays a central role in the therapeutic failure of CRC

Avoid direct contact with the peptide or solvent using bare hands

Effect of bacterial probiotics bio-encapsulated into Artemia franciscana on weight and length of the shortfin silverside (Chirostoma humboldtianum), and PCR-DGGE characterization of its intestinal bacterial community